Neuraminidase treatment enhances the lysolecithin induced intercellular adhesion of amoeba proteus.

P72: Hesperetine Nanoparticles Ameliorate Glial Activation and Reduce Demyelination Llevel of Rat Optic Chiasm in Lysolecithin-Iinduced Demyelination Model

Multiple sclerosis (MS) is one of the most autoimmune neurological and inflammatory disease in worldwide. Demyelination and disturbance of action potential conductance are regarded as main signs of MS disease. Hesperetin (Hst) is one of the flavonoid that have neuroprotective properties. The present study attempts to evaluate the effects of hesperetin or its nanoparticle on myelin repair and gl...

Effects of Blocking of Endogenous RHO Family GTP-Binding Proteins on Morphology, Adhesion and Locomotion of Amoeba Proteus.

Rho family GTP-binding proteins are known to control cellular processess associated with actin-based cytoskeleton such as cell migration, cytokinesis, endocytosis and exocytosis or muscle contraction [1]. While there is a number of data on the role of these proteins in higher Eukaryota, the studies on protozoans are practically limited to Dictyostelium that does not contain Rho-like and Cdc42-l...

Extracellular Calcium Changes the Morphology of Induced Pinocytosis in Amoeba proteus

In Amoeba proteus a typical induced pinocytosis is manifested after external application of different agents: aminoacides, proteins, monovalent cations. This pinocytosis is a kind of fluid-phase endocytosis driven by cortical cytoskeleton and may be compared to macropinocytosis in Dictyostelium discoideum in which large fluid-filled vesicles are formed (Maniak 2002). During induced pinocytosis ...

Minipodia, the Adhesive Structures Active in Locomotion and Endocytosis of Amoebae

Amoeba proteus cells, strains A and C t , with well pronounced motor polarity (the polytactic and orthotactic forms) develop dense coats of discrete minipodia which anchor them to the glass substratum. The scanning electron microscopy demonstrates that minipodia are surface microprotrusions about 0.5 μm thick and up to 8 μm long, covering mainly the middle-anterior area of the ventral cell surf...

Some Observations on the Behaviour of Amoeba proteus